Which of the following is a leukotriene inhibitor?

Ziflo, known generically as zileuton, is indeed a leukotriene inhibitor. It works by blocking the enzyme lipoxygenase, which plays a crucial role in the production of leukotrienes. Leukotrienes are inflammatory mediators that contribute to bronchoconstriction and mucus production, making them significant in the pathophysiology of asthma and allergic rhinitis. By inhibiting their formation, zileuton helps to reduce inflammation and improve airway function in patients suffering from these conditions.

Budesonide is a corticosteroid that primarily reduces inflammation in the airways rather than acting directly on leukotrienes. Albuterol is a bronchodilator that relaxes airway muscles but does not have any effect on leukotriene production or action. Prednisone is another corticosteroid that also serves to reduce inflammation but, like budesonide, does not function as a leukotriene inhibitor. Thus, zileuton stands out as the correct choice for its specific mechanism of targeting leukotriene pathways.