Which of the following is a late-phase mediator produced by Arachdonic acid?

The correct option refers to prostaglandins, which are indeed considered late-phase mediators produced from arachidonic acid. Arachidonic acid is a polyunsaturated fatty acid that serves as a precursor for the synthesis of various eicosanoids, including prostaglandins, leukotrienes, and thromboxanes.

Prostaglandins play a significant role in numerous physiological processes, including inflammation, pain, fever, and the regulation of various bodily functions. In the context of respiratory therapy and related conditions, prostaglandins can have effects on bronchial tone and vascular permeability, influencing airway responsiveness and inflammation.

In contrast, histamine and bradykinin are considered early-phase mediators and are typically involved in the immediate allergic response. Histamine is released by mast cells and causes bronchoconstriction, vasodilation, and increased vascular permeability. Bradykinin is a peptide that also contributes to inflammation but acts quickly.

Leukotrienes, while also derived from arachidonic acid and associated with airway inflammation and constriction, are mainly classified as early- to intermediate-phase mediators and are more directly involved in acute responses rather than the later stages of inflammation compared to prostaglandins. Thus, while leuk