How is Ribavirin typically delivered?

Ribavirin is typically delivered using a method known as SPAG, which stands for Small Particle Aerosol Generator. This delivery system is specifically designed to produce an aerosol that can be inhaled, allowing the medication to reach the respiratory tract effectively. SPAG is particularly useful in treating viral infections in the lungs, such as respiratory syncytial virus (RSV), which frequently affects infants and young children.

The use of SPAG allows for continuous aerosolization of ribavirin, enabling prolonged exposure to the medication in a hospital or clinical setting. This route of administration is important because ribavirin needs to target the respiratory mucosa to combat viral infections effectively. In contrast, while oral tablets and IV infusions are valid methods of drug delivery for many medications, they do not provide the same localized therapeutic effect in the lungs as inhalation therapy does. Similarly, traditional inhalers may not be suitable for ribavirin due to the specific particle size and delivery requirements necessary for effective treatment.