How does Prolastin work in the treatment of lung conditions?

Prolastin, which contains alpha-1 antitrypsin (AAT), is primarily used in the treatment of conditions like chronic obstructive pulmonary disease (COPD) and emphysema associated with alpha-1 antitrypsin deficiency. The key mechanism of action is that it inhibits elastase, an enzyme that breaks down elastin and other connective tissues in the lungs. This inhibition helps to protect lung tissue from damage that would otherwise be caused by the excessive breakdown of connective tissue, thereby preserving lung function and structure.

In patients with AAT deficiency, the lack of sufficient levels of this protein allows for unchecked activity of elastase, which can lead to severe lung damage and other complications. By administering Prolastin, the levels of alpha-1 antitrypsin in the blood are increased, providing a protective effect on the lung tissues by preventing elastase from breaking down the structural components of the lungs.

The other options do not accurately describe the function of Prolastin. While increased inflammation or mucus production can be aspects of lung disease, they are not mechanisms specific to the action of alpha-1 antitrypsin. The drug’s protective role against the breakdown of lung connective tissue is what makes it effective in